Treatments Against Wrinkling and Facial Aging

The human face is not a steady structure. It undergoes a slow changing course from the birth to death.

This structural change is very slow, but continuous. Some of the visual changes in this process impair the feeling of youth and strength, therefore can lead to some psychological consequences.

Generally the major concern of people about the aging face is the wrinkles. Wrinkles may be static (which are always apparent), or dynamic (which occur with facial animation or mimics). They can be deep or superficial, fine or blunt. These characteristics of the wrinkles determine what to do for treating them.

Currently, dynamic fine wrinkles are generally treated with botox applications. Dynamic wrinkles are the results of contraction of the underlying mimic muscles. Botox is a bacterial toxin, which acts by temporarily preventing the contraction of mimic muscles and therefore avoiding the overlying skin from wrinkling. When applied carefully, it eliminates the wrinkles without any disruption in facial expression or loss of mimics. Botox is most commonly used for the fine wrinkles of the forehead, crow’s feet area or the frown lines. It’s the gold standard treatment for these areas. Botox application is reversible, and should be repeated every 6 months for optimal results. It does not have any severe side effects. Ease of application, reasonable price and brilliant side-effect profile makes it the shining star of anti-wrinkle therapies.

Deeper wrinkles are generally static in nature, therefore they do not respond to Botox applications. This kind of wrinkling (or grooving) needs additional volume to simply “level up” the area. This additional volume can be supplied by synthetic injectible fillers or fat transfer. Use of injectable fillers is a more practical solution, but their effect lasts for a shorter time, which is generally about a year. They can be applied in the office within minutes, and don’t have a downtime. Fat injection, on the other hand, is a long lasting-partly permanent procedure but is more demanding. Fat transfer is done in the O.R., and has a one week downtime because of the swelling and bruising. Biology of the fat grafts is a very popular scientific topic today, and new discoveries about the advantages of their stem cell content are increasing everyday. We know for sure that, the stem cells in the fat grafts act a critical role in survival of the transferred fatty tissue and the improvement of the overlying skin quality.

For the treatment of fine wrinkles, poor skin quality and acne scars, fractional laser therapy is also a major tool. Lasers evaporate the superficial layer of the skin totally, and heat up the deeper skin layers, resulting in a totally resurfaced, clear skin. Laser resurfacing improves the blood circulation of the skin and strikingly rejuvenates the face.

One of the latest contributions of modern biotechnology to facial aesthetics is the PRP (Platelet-Rich-Plasma) application.PRP is a growth factor concentrate which is obtained from a person’s own blood. When this concentrate is directly injected through the skin, it triggers a sequence of biologic events which results in increased tissue turnover. This chain of reactions is similar to what happens in the wound healing period. The factors promote renewal of the cells, collagen and improves the blood supply to the skin. As these factors are isolated from the person’s own blood, this application does not have any side effects.

As it can easily be understood, there are different ways to deal with the aging skin. The selection of the right tool to fight against a particular skin disorder, is the main role of the physician. There are pros and cons of each technique so they should be employed for the correct purpose. A deformity that will completely disappear with botox may not be a good reason for laser, or a filler may not give the desired result. The right thing to do is asking to be informed about the procedure, but also leaving the decision to the professional.

Ask to Doctor

Please feel free to ask any questions about treatments against wrinkling and facial aging

  • As soon as we receive your message, we will send you a confirmation mail.
  • Our experienced Patient Coordinators will get back to you in the shortest time.
  • All your questions will be answered.
(Please write your country code)
(if needed)



Take photo(s) for your relevant area with your smartphone. Then get results.



Request an appointment using our online form.

Reviews of the past patients who had been operated already


“Great experience throughout!”

Treatment Received:

Five star

Reviewed 17 Apr 2016
Review confirmed by phone.

“I booked in for my rhinoplasty operarion on the 6th January. At the consultation (day before) he spoke about what needed to be done to my nose, he put everything into words of what needed done, which I knew and couldn’t explain myself. It is now 3 months post op I am very happy with the result which is so natural already, noone can tell its a ‘done’ nose, there is still them for it to improve further. The OVERALL service was excelllent throughout. I would definately come back to Dr Kerem if any future surgeries are necessary!

Great experience throughout! The clinic was clean, anasthesia was easy, I was asleep before I got to the operating theatre. After the operation, when I woke up I was given some lovely vegetarian food. All staff were polite and friendly, they looked after me all night, giving me ice and pain prevention. X”


“I am super happy with the look of both my breast and tummy”

Treatment Received:
Mommy Makeover

Five star

Reviewed 08 Feb 2016
Review verified by phone.

“I am Kani from Iraq I had a surgery on 30/11/ 2015. And I’m very satisfied with my results. Dr. Metin Kerem has changed my body for 200% better. I had saggy breasts, fat rolls around my waist and a tummy that looked like I gave birth to ten children, now just everything is perfect, breasts very natural (implants and fat)! My fat rolls are gone. I have a much slimmer waistline and my tummy looks fantastic, flat and even the stretchmarks are 90% gone. Everybody of the team has been very nice they helped me a lot especially Ferve! Feel perfect now.

I had a great experience with Dr. Metin and the staff they are very friendly. Everybody was very kind and professional. Choice of this clinic was the right decision to make I am super happy with the look of both my breast and tummy. The scars are very delicate. I would recommend Dr.Metinto any of my friends or family. Thank you so much Doctor.
And a big thank you to Ferve amazing people.
Great experience overall .”


“Lifted my confidence as I look and feel good”

Treatment Received:
Fat Transfer

Five star

Reviewed 07 Dec 2015
Review verified by phone.

“Had a liposuction and fat transfer to the upper part of my bum on the 17th of November it’s almost a month since my treatment, it had lifted my confidence I feel and look good glad I did it the experience was amazing.

It took me almost 6 months to go through with the treatment kept consulting with ferv whiles in the uk I kept changing my mind,ferv was ever so patient never forceful and very attentive.

When I finally made a solid decision she booked my treatment and my accommodation along with transfer that eased the stress.

My hotel was very nice along with the staff, I had a nice big room. I hightly recommend Harbiye residence I intend to stay there again on my next visit.

The clinic was very clean and accommodating everything looks better in person Dr kerem explained everything clearly set by set him and is staffs were very welcoming and professional.

The hospital was very clean the staff were very helpful and attentive I felt spoilt 🙂

I took a big risk going on my own
But throughout my experience I never felt alone
I enjoyed my experience!

Experience it for yourself you won’t regret it!

I’m back again in may next year with a few other we all having something done:)
If you want to go in may a feel a little worried you can always come along with me
But as I said I went alone and I felt safe.”

Dr. Metin Kerem Plastic Surgery Center
A hi-tech boutique of plastic surgery, in a central and prestigious location in Istanbul.

European Board Certified Plastic Surgeon, Dr. Metin Kerem is in charge of all invasive-and non invasive procedures himself, on a patient-oriented basis. All minimal invasive procedures are undertaken in the clinic, while invasive surgical procedures are done in a fully equipped hospital, specially designed for plastic surgery procedures. Dr. Metin Kerem welcomes patients from all over the world, for an exciting touch to face and body aesthetics.